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Article

six3 acts upstream of foxQ2 in labrum and neural development in the spider Parasteatoda tepidariorum.

Development genes and evolution - 1 Mar 2020

Schacht Magdalena Ines, Schomburg Christoph, Bucher Gregor

Abstract excerpt

Anterior patterning in animals is based on a gene regulatory network, which comprises highly conserved transcription factors like six3, pax6 and otx. More recently, foxQ2 was found to be an ancestral component of this network but its regulatory interactions showed evolutionary differences. In most animals, foxQ2 is a downstream target of six3 and knockdown leads to mild or no epidermal phenotypes. In contrast, in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32040712
DOI: 10.1007/s00427-020-00654-9
PMCID: PMC7128001

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