Article
An O antigen can interfere with the function of the Yersinia pseudotuberculosis invasin protein.
Molecular microbiology - 1 Feb 1991
Voorhis D L, Dillon S, Formal S B, Isberg R R
Abstract excerpt
Escherichia coli strains harbouring the Yersinia pseudotuberculosis inv gene are able to enter cultured mammalial cells. We show here that this property is not shared by all enteric bacteria, since Shigella flexneri 2a cured of its virulence-associated plasmid and harbouring the inv gene is unable to enter mammalian cells efficiently. Mapping studies showed that the region of the chromosome responsible for this...
Topics
- Adhesins, Bacterial
- Antigens, Bacterial
- Antigens, Surface
- Bacterial Proteins
- Humans
- O Antigens
- Phenotype
- Shigella flexneri
- Tumor Cells, Cultured
- Virulence
- Yersinia pseudotuberculosis
