Article
Voltage-gated sodium channels: action players with many faces.
Annals of medicine - 1 Jan 2006
Koopmann Tamara T, Bezzina Connie R, Wilde Arthur A M
Abstract excerpt
Voltage-gated sodium channels are responsible for the upstroke of the action potential and thereby play an important role in propagation of the electrical impulse in excitable tissues like muscle, nerve and the heart. Duplication of the sodium channels encoding genes during evolution generated the sodium channel gene family with the different isoforms differing in biophysical properties and tissue distribution....
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