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Article

14-3-3 protein binds to the low molecular weight neurofilament (NFL) mRNA 3' UTR.

Molecular and cellular neurosciences - 1 Jan 2007

Ge Wei-Wen, Volkening Kathryn, Leystra-Lantz Cheryl, Jaffe Howard, Strong Michael J

Abstract excerpt

We have previously reported that altered stability of low molecular weight neurofilament (NFL) mRNA in lumbar spinal cord homogenates in amyotrophic lateral sclerosis (ALS) is associated with altered expression of trans-acting 3' UTR mRNA binding proteins. We have identified two hexanucleotide motifs as the main cis elements and, using LC/MS/MS of peptide digests of NFL 3' UTR interacting proteins from human...

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Identifiers

PMID: 17098443
DOI: 10.1016/j.mcn.2006.10.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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