Article
Aberrant limbic brain structures in young individuals at risk for mental illness.
Psychiatry and clinical neurosciences - 1 May 2020
Nogovitsyn Nikita, Souza Roberto, Muller Meghan, Srajer Amelia, Metzak Paul D, Hassel Stefanie, Ismail Zahinoor, Protzner Andrea, Bray Signe L, Lebel Catherine, MacIntosh Bradley J, Goldstein Benjamin I, Wang JianLi, Kennedy Sidney H, Addington Jean, MacQueen Glenda M
Abstract excerpt
AIM: Alterations in limbic structures may be present before the onset of serious mental illness, but whether subfield-specific limbic brain changes parallel stages in clinical risk is unknown. To address this gap, we compared the hippocampus, amygdala, and thalamus subfield-specific volumes in adolescents at various stages of risk for mental illness. METHODS: MRI scans were obtained from 182 participants (aged...
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