Article
Inhibition of receptor internalization attenuates the TNFalpha-induced ROS generation in non-phagocytic cells.
Biochemical and biophysical research communications - 29 Dec 2006
Woo Chang-Hoon, Kim Tae-Hee, Choi Jung-A, Ryu Ho-Cheol, Lee Jung Eun, You Hye-Jin, Bae Yun-Soo, Kim Jae-Hong
Abstract excerpt
Reactive oxygen species (ROS) are important regulatory molecules implicated in the signaling cascade triggered by tumor necrosis factor (TNF)alpha, although the events through which TNFalpha induces ROS generation are not well characterized. Here, we report that TNFalpha-induced ROS production wa...
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