Article
Role of ribosome release in the basal level of expression of the Escherichia coli gene pheA.
Journal of general microbiology - 1 Mar 1991
Gavini N, Pulakat L
Abstract excerpt
In Escherichia coli, the expression of the phenylalanine biosynthetic operon pheA is regulated by an attenuation mechanism. In the presence of excess phenylalanine, gene expression was decreased to 10% of the fully deattenuated level. To understand the factors that determine the basal level of pheA expression, we examined the role of ribosome release from the leader peptide stop codon UGA. The transcriptional...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Codon
- DNA, Bacterial
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation