Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germ line mutations of the HMGA2 gene are rare among the general population.

Anticancer research - 1 Jan 2000

von Ahsen Inga, Rogalla Piere, Bullerdiek Jörn

Abstract excerpt

Proteins encoded by the HMGA family are architectural transcription factors, which induce conformational changes in the DNA and thus influence gene expression. Despite the obvious association of the expression of high mobility group protein genes with human cancer, very little is known about the variation of the HMGA proteins within human populations. Therefore, the coding regions of HMGA2 from 87 normal healthy...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HMGA2 gene
Share to Germ-Line Mutation
Share to HMGA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 17094442

Genes

HMGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germ line mutations of the HMGA2 gene are rare among the general population.PMID 17094442Read ↗

HMGI(Y) and HMGI-C DysregulationSemantic proximity Read ↗

Prognostic value of high mobility group protein A2 (HMGA2) over-expression in cancer progressionSemantic proximity Read ↗

Clinical and Molecular Investigation of Familial Multiple Lipomatosis: Variants in the HMGA2 GeneSemantic proximity Read ↗

Roles of HMGA proteins in cancer.Semantic proximity Read ↗

Uterine leiomyomata and decreased height: a common HMGA2 predisposition allele.Semantic proximity Read ↗

HMGA2 gene polymorphisms and Wilms tumor susceptibility in Chinese children: a four-center case-control study.Semantic proximity Read ↗

The genetic variation of the human HMGB1 gene.Semantic proximity Read ↗

Association of deletion polymorphism rs10573247 in the HMGA2 gene with the risk of breast cancer: bioinformatic and experimental analyses.Semantic proximity Read ↗

No association between HMGB1 polymorphisms and cancer risk: evidence from a meta-analysis.Semantic proximity Read ↗

HMGA1 protein expression in familial breast carcinoma patientsSemantic proximity Read ↗

Insights into the regulation of a common variant of HMGA2 associated with human height during embryonic development.Semantic proximity Read ↗

The High Mobility Group A1 ( HMGA1 ) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 ( MMP-2 ) in a subset of tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.