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Article

The strong correlation between ADAM33 expression and airway inflammation in chronic obstructive pulmonary disease and candidate for biomarker and treatment of COPD.

Scientific reports - 30 Nov 2021

Fachri Muhammad, Hatta Mochammad, Massi Muhammad Nasrum, Santoso Arif, Wikanningtyas Tri Ariguntar, Dwiyanti Ressy, Junita Ade Rifka, Primaguna Muhammad Reza, Sabir Muhammad

Abstract excerpt

Airway inflammation in patients with chronic obstructive pulmonary disease (COPD) is an amplified response of the normal immune system that occurs as a result of chronic irritation by toxic substances, such as cigarette smoke. This leads to the characteristic pathological changes in the inflammatory cells of COPD patients. ADAM33 has been reported to be involved in the pathogenesis of COPD in East Asia by...

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PMID: 34848800
DOI: 10.1038/s41598-021-02615-2
PMCID: PMC8632976

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