Article
Banking on ATM as a new target in metabolic syndrome.
Cell metabolism - 1 Nov 2006
Shoelson Steven E
Abstract excerpt
In this issue of Cell Metabolism, Semenkovich and his colleagues show that ATM, a protein well known for its roles in the cellular response to DNA breaks, may also be linked to metabolic and cardiovascular diseases (Schneider et al., 2006). ATM seemingly does this by inhibiting JNK, a stress kinase involved in inflammation with related effects in insulin resistance and atherosclerosis. In an interesting twist,...
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