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Membrane-enclosed Pseudomonas quinolone signal attenuates bacterial virulence by interfering with quorum sensing

5 Oct 2023

Abstract excerpt

ABSTRACT Outer membrane vesicle (OMV)-delivered Pseudomonas quinolone signal (PQS) plays a critical role in cell–cell communication in Pseudomonas aeruginosa . However, the functions and mechanisms of membrane-enclosed PQS in interspecies communication in microbial communities are not clear. Here, we demonstrate that PQS delivered by both OMVs from P. aeruginosa and liposome reduces the competitiveness of...

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PMID: 37796010
DOI: 10.1128/aem.01184-23

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