Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).

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Article

Cloning of an alternate form of vascular cell adhesion molecule-1 (VCAM1).

The Journal of biological chemistry - 15 Apr 1991

Hession C, Tizard R, Vassallo C, Schiffer S B, Goff D, Moy P, Chi-Rosso G, Luhowskyj S, Lobb R, Osborn L

Abstract excerpt

Vascular cell adhesion molecule-1 (VCAM1) of the Ig superfamily is induced by the inflammatory cytokines interleukin-1 and tumor necrosis factor on human umbilical vein endothelial cells (HUVECs). It binds to mononuclear leukocytes via the integrin VLA-4. We have cloned and expressed a cDNA encoding a new form of human VCAM1 containing an additional Ig homologous domain inserted between the third and fourth...

Topics

Amino Acid Sequence
Base Sequence
Cell Adhesion Molecules
Cells, Cultured
Cloning, Molecular
DNA
Endothelium, Vascular
Female
Genetic Variation
Genetic Vectors
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Nucleic Acid Hybridization

Oligonucleotide Probes

Polymerase Chain Reaction

Pregnancy

RNA, Messenger

Sequence Homology, Nucleic Acid

Source

Open in PubMed

Identifiers

PMID: 1707873

Genes

VCAM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1707873-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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