Article
Biodiversity of CYP51 in trypanosomes.
Biochemical Society transactions - 1 Dec 2006
Lepesheva G I, Hargrove T Y, Ott R D, Nes W D, Waterman M R
Abstract excerpt
Sterol 14alpha-demethylases (CYP51) are metabolic cytochromes P450, found in each biological kingdom. They catalyse a single three-step reaction included in all sterol biosynthetic pathways. Plant CYP51s have strict preference towards their physiological substrate O (obtusifoliol), which is C-4-m...
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