Article
Disturbed frontal gyrification within families affected with schizophrenia.
Journal of psychiatric research - 1 Nov 2007
Falkai Peter, Honer William G, Kamer Thomas, Dustert Simone, Vogeley Kai, Schneider-Axmann Thomas, Dani Indra, Wagner Michael, Rietschel Marcella, Müller Daniel J, Schulze Thomas G, Gaebel Wolfgang, Cordes Joachim, Schönell Helmut, Schild Hans H, Block Wolfgang, Träber Frank, Steinmetz Helmuth, Maier Wolfgang, Tepest Ralf
Abstract excerpt
OBJECTIVE: Recently, in a post-mortem and a subsequent structural MR study, a significantly increased gyrification index (GI) was demonstrated in the frontal lobe in individuals with schizophrenia. To examine whether frontal lobe hypergyria is region-specific and whether this might be a suitable endophenotype in the search for the genetic basis of schizophrenia, the frontal as well as parieto-occipital GI were...
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