Article
Relation between cerebrospinal fluid, gray matter and white matter changes in families with schizophrenia.
Journal of psychiatric research - 1 Oct 2006
Schneider-Axmann Thomas, Kamer Thomas, Moroni Manuel, Maric Nadja, Tepest Ralf, Dani Indra, Honer William G, Scherk Harald, Rietschel Marcella, Schulze Thomas G, Müller Daniel J, Cordes Joachim, Schönell Helmut, Steinmetz Helmuth, Gaebel Wofgang, Vogeley Kai, Kühn Kai-Uwe, Wagner Michael, Maier Wolfgang, Träber Frank, Block Wolfgang, Schild Hans H, Falkai Peter
Abstract excerpt
BACKGROUND: Gray matter reduction and ventricular enlargement belong to the best replicated findings in schizophrenia. Brain morphologic changes were also found in non-schizophrenic family members (FM). The intention of this study was to examine whether non-psychotic first-degree relatives reveal similar morphologic changes as schizophrenic patients and how state of genetic loading contribute to these...
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