Article
Admixture in Mexico City: implications for admixture mapping of type 2 diabetes genetic risk factors.
Human genetics - 1 Feb 2007
Martinez-Marignac Veronica L, Valladares Adan, Cameron Emily, Chan Andrea, Perera Arjuna, Globus-Goldberg Rachel, Wacher Niels, Kumate Jesús, McKeigue Paul, O'Donnell David, Shriver Mark D, Cruz Miguel, Parra Esteban J
Abstract excerpt
Admixture mapping is a recently developed method for identifying genetic risk factors involved in complex traits or diseases showing prevalence differences between major continental groups. Type 2 diabetes (T2D) is at least twice as prevalent in Native American populations as in populations of European ancestry, so admixture mapping is well suited to study the genetic basis of this complex disease. We have...
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