Article
The S Segment of Punta Toro Virus ( Bunyaviridae , Phlebovirus ) Is a Major Determinant of Lethality in the Syrian Hamster and Codes for a Type I Interferon Antagonist
27 Dec 2006
Abstract excerpt
Two strains of Punta Toro virus (PTV), isolated from febrile humans in Panama, cause a differential pathogenesis in Syrian hamsters, which could be a useful model for understanding the virulence characteristics and differential outcomes in other phleboviral infections such as Rift Valley fever virus. Genetic reassortants produced between the lethal Adames (A/A/A) and nonlethal Balliet (B/B/B) strains were used in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
