Article
The impact on coronary artery disease of common polymorphisms known to modulate responses to pathogens.
Annals of human genetics - 1 Nov 2006
O'Halloran A M, Stanton A, O'Brien E, Shields D C
Abstract excerpt
There are two distinct models to explain how genetic variants contributing to cardiovascular disease may have arisen. Firstly, variants may result from random, initially neutral, mutations whose effects are largely revealed in post-reproductive individuals in industrialized societies. Alternative...
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