Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.

Annals of hematology - 1 Jan 2007

Nadir Y, Hoffman R, Brenner B

Abstract excerpt

Hyperhomocysteinemia (HHC) is a known risk factor for venous and arterial thrombosis. Thrombophilia workup includes the level of homocysteine and other related parameters such as: vitamin B(12), folic acid, and methylenetetrahydrofolate reductase (MTHFR) C677T genotype. As the levels of homocysteine, vitamin B(12), folic acid, and MTHFR C677T genotype are linked biochemically, we hypothesized that a statistical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Folic Acid
Share to Homocysteine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperhomocysteinemia

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Pregnancy

Share to Thrombosis

Share to Vitamin B 12

Source

Identifiers

PMID: 17043779
DOI: 10.1007/s00277-006-0194-1

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of homocysteine, vitamin B12, folic acid, and MTHFR C677T in patients with a thrombotic event or recurrent fetal loss.PMID 17043779Read ↗

Thrombophilias and recurrent pregnancy loss: a critical appraisal of the literature.Semantic proximity Read ↗

Hypercoagulable thrombophilic defects and hyperhomocysteinemia in patients with recurrent pregnancy loss.Semantic proximity Read ↗

Clinical significance of determining plasma homocysteine: case-control study on arterial and venous thrombotic patients.Semantic proximity Read ↗

Association of MTHFR A1298C polymorphism (but not of MTHFR C677T) with elevated homocysteine levels and placental vasculopathies.Semantic proximity Read ↗

The importance of folate, vitamins B6 and B12 for the lowering of homocysteine concentrations for patients with recurrent pregnancy loss and MTHFR mutations.Semantic proximity Read ↗

Hyperhomocysteinemia increases the risk of venous thrombosis independent of the C677T mutation of the methylenetetrahydrofolate reductase gene in selected Brazilian patients.Semantic proximity Read ↗

Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes.Semantic proximity Read ↗

The risk of venous thromboembolism associated with the factor V Leiden mutation and low B-vitamin status.Semantic proximity Read ↗

Homocysteine, MTHFR and risk of venous thrombosis: a meta-analysis of published epidemiological studies.Semantic proximity Read ↗

Clinical Implications of Methylenetetrahydrofolate Reductase Mutations and Plasma Homocysteine Levels in Patients with Thromboembolic OcclusionSemantic proximity Read ↗

Hyperhomocysteinemia as a risk factor for venous thrombosis.Semantic proximity Read ↗

A woman with five consecutive fetal deaths: case report and retrospective analysis of hyperhomocysteinemia prevalence in 100 consecutive women with recurrent miscarriages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.