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Article

Nearly all hereditary paragangliomas in the Netherlands are caused by two founder mutations in the SDHD gene.

Genes, chromosomes & cancer - 1 Jul 2001

Taschner P E, Jansen J C, Baysal B E, Bosch A, Rosenberg E H, Bröcker-Vriends A H, van Der Mey A G, van Ommen G J, Cornelisse C J, Devilee P

Abstract excerpt

Hereditary paragangliomas or glomus tumors are usually benign slow-growing tumors in the head and neck region. The inheritance pattern of hereditary paraganglioma is autosomal dominant with imprinting. Recently, we have identified the SDHD gene encoding subunit D of the mitochondrial respiratory chain complex II as one of the genes involved in hereditary paragangliomas. Here, we demonstrate that two founder...

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Source

Identifiers

PMID: 11391798
DOI: 10.1002/gcc.1144

Genes

SDHD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Nearly all hereditary paragangliomas in the Netherlands are caused by two founder mutations in the SDHD gene.PMID 11391798Read ↗

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Identification of novel SDHD mutations in patients with phaeochromocytoma and/or paraganglioma.Semantic proximity Read ↗

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