Article
Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6.
Journal of bacteriology - 1 Jan 2007
Lanie Joel A, Ng Wai-Leung, Kazmierczak Krystyna M, Andrzejewski Tiffany M, Davidsen Tanja M, Wayne Kyle J, Tettelin Hervé, Glass John I, Winkler Malcolm E
Abstract excerpt
Streptococcus pneumoniae (pneumococcus) is a leading human respiratory pathogen that causes a variety of serious mucosal and invasive diseases. D39 is an historically important serotype 2 strain that was used in experiments by Avery and coworkers to demonstrate that DNA is the genetic material. Although isolated nearly a century ago, D39 remains extremely virulent in murine infection models and is perhaps the...
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