Article
Mosaic genes and mosaic chromosomes-genomic variation in Streptococcus pneumoniae.
International journal of medical microbiology : IJMM - 1 Sept 2004
Brückner Reinhold, Nuhn Michael, Reichmann Peter, Weber Beate, Hakenbeck Regine
Abstract excerpt
The genome sequences of two strains of Streptococcus pneumoniae, one of the major human pathogens, are currently available: that of the nonencapsulated laboratory strain R6, the origin of which dates back to the early 20th century, and of the serotype 4 TIGR strain isolated recently. The two genomes are not only different in size (2 versus 2.16 Mb) but differ also by approximately 10% of their genes, many of...
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