Article
Integration of curated databases to identify genotype-phenotype associations.
BMC genomics - 12 Oct 2006
Goh Chern-Sing, Gianoulis Tara A, Liu Yang, Li Jianrong, Paccanaro Alberto, Lussier Yves A, Gerstein Mark
Abstract excerpt
BACKGROUND: The ability to rapidly characterize an unknown microorganism is critical in both responding to infectious disease and biodefense. To do this, we need some way of anticipating an organism's phenotype based on the molecules encoded by its genome. However, the link between molecular composition (i.e. genotype) and phenotype for microbes is not obvious. While there have been several studies that address...
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