Article
The case for a genetic predisposition to serrated neoplasia in the colorectum: hypothesis and review of the literature.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2006
Young Joanne, Jass Jeremy R
Abstract excerpt
In recent years, an alternative pathway of colorectal cancer development has been described in which serrated polyps replace the traditional adenoma as the precursor lesion. Importantly, serrated polyps and a subset of colorectal cancer show largely nonoverlapping mutation profiles to those found...
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