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Article

MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family.

Journal of molecular biology - 5 Jan 1991

Wiesenberger G, Link T A, von Ahsen U, Waldherr M, Schweyen R J

Abstract excerpt

When present in high copy number plasmids, the nuclear genes MRS3 and MRS4 from Saccharomyces cerevisiae can suppress the mitochondrial RNA splicing defects of several mit- intron mutations. Both genes code for closely related proteins of about Mr 32,000; they are 73% identical. Sequence comparisons indicate that MRS3 and MRS4 may be related to the family of mitochondrial carrier proteins. Support for this notion...

Topics

Amino Acid Sequence
Base Sequence
Blotting, Northern
Blotting, Southern
Carrier Proteins
Cation Transport Proteins
Chromosome Mapping
Chromosomes, Fungal
Fungal Proteins
Gene Expression Regulation, Fungal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, Fungal

Genes, Suppressor

Mitochondria

Mitochondrial Proteins

Molecular Sequence Data

Phenotype

Plasmids

RNA

Source

Identifiers

PMID: 1703236
DOI: 10.1016/0022-2836(91)90608-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1703236-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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MRS3 and MRS4, two suppressors of mtRNA splicing defects in yeast, are new members of the mitochondrial carrier family.PMID 1703236Read ↗

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