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Article

Cap-dependent and hepatitis C virus internal ribosome entry site-mediated translation are modulated by phosphorylation of eIF2alpha under oxidative stress.

The Journal of general virology - 1 Nov 2006

MacCallum Paul R, Jack Samantha C, Egan Philip A, McDermott Benjamin T, Elliott Richard M, Chan Shiu-Wan

Abstract excerpt

Chronic hepatitis C is often associated with oxidative stress. Hepatitis C virus (HCV) utilizes an internal ribosome entry site (IRES) element for translation, in contrast to cap-dependent translation of the majority of cellular proteins. To understand how virus translation is modulated under oxi...

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Identifiers

PMID: 17030858
DOI: 10.1099/vir.0.82051-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17030858-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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