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Article

Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes.

Journal of autoimmunity - 1 Sept 2006

Alper Chester A, Husain Zaheed, Larsen Charles E, Dubey Devendra P, Stein Rosanne, Day Caitlin, Baker Alissa, Beyan Huriya, Hawa Mohammed, Ola Thomas O, Leslie R David

Abstract excerpt

Incomplete intrinsic penetrance is the failure of some genetically susceptible individuals (e.g., monozygotic twins of those who have a trait) to exhibit that trait. For the first time, we examine penetrance of susceptibility genes for multiple MHC gene-determined traits in the same subjects. Serum levels of IgA, IgD, IgG3, but not IgG4, in 50 pairs of monozygotic twins discordant for type 1 diabetes (T1D)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17029885
DOI: 10.1016/j.jaut.2006.07.007
PMCID: PMC1810396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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