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Article

Common mutations at the homocysteine metabolism pathway and pediatric stroke.

Thrombosis research - 15 Apr 2001

Akar N, Akar E, Ozel D, Deda G, Sipahi T

Abstract excerpt

Heterozygosity and/or homozygosity for mutations at the genes of the enzymes involved in homocysteine metabolism may confer an increased risk for thrombosis by causing hyperhomocysteinemia. Although the mutations related to homocysteine metabolism possibly increase the risk of stroke, the data are conflicting and there are very few reports linking these defects to acute stroke in children. We aimed to study the...

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Source

Identifiers

PMID: 11323021
DOI: 10.1016/s0049-3848(01)00226-2

Genes

MTHFR
MTRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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