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Article

Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review.

1 Jan 2006

Abstract excerpt

Transcriptional silencing of tumor suppressor genes, associated with DNA methylation, is a common epigenetic event in hematologic malignancies. Although DNA hypermethylation of CpG islands is well described in acute leukemias and myelodysplastic syndromes, much less is known of the specific methylation changes that commonly occur in follicular B cell lymphomas. Earlier methylation studies of follicular lymphoma...

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PMID: 17026765
DOI: 10.1186/1476-4598-5-44

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