Article
Decreased serum and red blood cell kynurenic acid levels in Alzheimer's disease.
Neurochemistry international - 1 Jan 2007
Hartai Zsuzsanna, Juhász Anna, Rimanóczy Agnes, Janáky Tamás, Donkó Teodóra, Dux László, Penke Botond, Tóth Gábor K, Janka Zoltán, Kálmán János
Abstract excerpt
Kynurenine aminotransferases (KAT I and KAT II) are responsible for the transamination of kynurenine (KYN) to form kynurenic acid (KYNA), an excitatory amino acid receptor antagonist. Since these members of the kynurenine pathway (KP) are proposed to be involved in the pathogenesis of Alzheimer's...
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