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Article

Effects of THBS3, SPARC and SPP1 expression on biological behavior and survival in patients with osteosarcoma

5 Oct 2006

Abstract excerpt

BACKGROUND: Osteosarcoma is a very aggressive tumor with a propensity to metastasize and invade surrounding tissue. Identification of the molecular determinants of invasion and metastatic potential may guide the development of a rational strategy for devising specific therapies that target the pathways leading to osteosarcoma. METHODS: In this study, we used pathway-focused low density expression cDNA arrays to...

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PMID: 17022822
DOI: 10.1186/1471-2407-6-237

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