Article
Induction of expression of hfq by DksA is essential for Shigella flexneri virulence.
Molecular microbiology - 1 Oct 2006
Sharma Ashima K, Payne Shelley M
Abstract excerpt
Hfq plays an important role in cellular physiology by regulating the expression of several genes. Hfq synthesis in Escherichia coli is subject to auto-repression at translational level. Studies with Shigella flexneri show that hfq transcription is regulated by a pleiotropic regulator, DksA. Comparison of gene expression profiles of wild type and dksA mutant S. flexneri determined that hfq expression was reduced...
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