Article
[Isepamycin in prophylaxis and treatment of experimental plague due to FI+ and FI- variants of plague microbe].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 2005
Smorodinova Iu V, Shcherbaniuk A I, Ryzhko I V, Moldavan I A
Abstract excerpt
The efficacy of isepamycin vs. other aminoglycosides was studied in vitro and on albino mice with experimental plague due to natural antigen valuable strains of the plague microbe and the pathogen variants deprived of the ability to produce the capsular antigen fraction I (FI- phenotype). The MICs of isepamycin for the strains of the plague microbe (20 FI+ and 20FI-) were 1.0-4.0 mg\l, that did not differ from...
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