Article
[Ofloxacin efficacy in the prophylaxis and treatment of experimental plague due to antigen complete and defective strains of the pathogen].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] - 1 Jan 2002
Samokhodkina E D, Shcherbaniuk A I, Ryzhko I V, Tsuraeva R I, Skalyga E Iu
Abstract excerpt
Strains of the plague microbe, antigen complete and defective by fraction I and mouse toxin had the same in vitro susceptibility to ofloxacin (MIC 0.08 mg/L). The drug was superior in its activity to pefloxacin and especially nalidixic acid. In the experiments with albino mice (prophylaxis, 5 days) the ofloxacin efficacy was lower when the infection was due to the plague microbe strains deprived of the ability to...
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