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Article

Expression Profiling of the Ovarian Surface Kinome Reveals Candidate Genes for Early Neoplastic Changes

1 Dec 2009

Abstract excerpt

OBJECTIVES: We tested the hypothesis that co-coordinated up-regulation or down-regulation of several ovarian cell surface kinases may provide clues for better understanding of the disease and help in rational design of therapeutic targets. STUDY DESIGN: We compared the expression signature of 69 surface kinases in normal ovarian surface epithelial cells (OSE), with OSE from patients at high risk and with ovarian...

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PMID: 19956396
DOI: 10.1593/tlo.09199

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