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Article

Irradiation exacerbates cortical cytopathology in the Eker rat model of tuberous sclerosis complex, but does not induce hyperexcitability.

Epilepsy research - 1 Jan 2007

Tschuluun Naranzogt, Wenzel H Jürgen, Schwartzkroin Philip A

Abstract excerpt

Tuberous sclerosis complex (TSC) is an autosomal dominant disorder characterized by multi-organ pathologies. Most TSC patients exhibit seizures, usually starting in early childhood. The neuropathological hallmarks of the disease - cortical tubers, containing cytopathological neuronal and glial cell types - appear to be the source of seizure initiation. However, the contribution of these aberrant cell populations...

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Source

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Identifiers

PMID: 17011168
DOI: 10.1016/j.eplepsyres.2006.08.003
PMCID: PMC1905148

Genes

TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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