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Transcriptomic and genomic analysis of human hepatocellular carcinomas and hepatoblastomas†

27 Sept 2006

Abstract excerpt

This study analyzed gene expression patterns and global genomic alterations in hepatocellular carcinomas (HCC), hepatoblastomas (HPBL), tissue adjacent to HCC and normal liver tissue derived from normal livers and hepatic resections. We found that HCC and adjacent non-neoplastic cirrhotic tissue have considerable overlap in gene expression patterns compared to normal liver. Several genes including Glypican 3,...

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PMID: 17006932
DOI: 10.1002/hep.21328

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