Article
Quantification of hepatitis B virus genomes and infectivity in human serum samples.
Transfusion - 1 Oct 2006
Hsia Chu Chieh, Purcell Robert H, Farshid Mahmood, Lachenbruch Peter A, Yu Mei-Ying W
Abstract excerpt
BACKGROUND: Hepatitis B virus (HBV) infections are still a major health issue, with approximately 350 million people chronically infected with HBV worldwide. Information about the minimum copy number of HBV genomes required for infection would be useful as a reference for drug and vaccine development; for monitoring HBV patients during treatment; for screening of blood, organ, and tissue donors; and for...
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