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A Stereological Analysis of the Response of Spermatogenesis to an Acute Inflammatory Episode in Adult Rats

14 Dec 2006

Abstract excerpt

Male fertility is inhibited by inflammatory disease, but the mechanisms responsible are poorly defined. The effects of acute systemic inflammation induced by a single IP injection of lipopolysaccharide (LPS) on spermatogenic function in adult male rats were investigated using detailed stereological analysis. The earliest effect observed was a significant maturational delay of meiosis during the leptotene/zygotene...

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PMID: 16988326
DOI: 10.2164/jandrol.106.000752

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