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Increased Apoptosis Occurring During the First Wave of Spermatogenesis Is Stage-Specific and Primarily Affects Midpachytene Spermatocytes in the Rat Testis1

1 Feb 2004

Abstract excerpt

The physiological apoptosis that occurs in immature testis appears to be necessary for the maturation of this tissue. Thus, inhibition of the early apoptotic wave associated with the first round of spermatogenesis is followed by accumulation of spermatogonia and infertility later in life. To identify the cell types undergoing apoptosis in immature rat testis and to characterize the relationship between this...

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PMID: 14522836
DOI: 10.1095/biolreprod.103.018390

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