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Article

Demand theory of gene regulation. II. Quantitative application to the lactose and maltose operons of Escherichia coli.

Genetics - 1 Aug 1998

Savageau M A

Abstract excerpt

Induction of gene expression can be accomplished either by removing a restraining element (negative mode of control) or by providing a stimulatory element (positive mode of control). According to the demand theory of gene regulation, which was first presented in qualitative form in the 1970s, the negative mode will be selected for the control of a gene whose function is in low demand in the organism's natural...

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Identifiers

PMID: 9691028
DOI: 10.1093/genetics/149.4.1677
PMCID: PMC1460280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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