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Article

The genetic basis of thermal reaction norm evolution in lab and natural phage populations.

PLoS biology - 1 Jul 2006

Knies Jennifer L, Izem Rima, Supler Katie L, Kingsolver Joel G, Burch Christina L

Abstract excerpt

Two major goals of laboratory evolution experiments are to integrate from genotype to phenotype to fitness, and to understand the genetic basis of adaptation in natural populations. Here we demonstrate that both goals are possible by re-examining the outcome of a previous laboratory evolution experiment in which the bacteriophage G4 was adapted to high temperatures. We quantified the evolutionary changes in the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16732695
DOI: 10.1371/journal.pbio.0040201
PMCID: PMC1472247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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