Use of analgesics and nonsteroidal anti-inflammatory drugs, genetic predisposition, and bladder cancer risk in Spain.

doi:10.1158/1055-9965.EPI-06-0038

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Use of analgesics and nonsteroidal anti-inflammatory drugs, genetic predisposition, and bladder cancer risk in Spain.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Sept 2006

Fortuny Joan, Kogevinas Manolis, Garcia-Closas Montserrat, Real Francisco X, Tardón Adonina, Garcia-Closas Reina, Serra Consol, Carrato Alfredo, Lloreta Josep, Rothman Nat, Villanueva Cristina, Dosemeci Mustafa, Malats Núria, Silverman Debra

Abstract excerpt

BACKGROUND: We assessed use of nonaspirin nonsteroidal anti-inflammatory drugs (NSAID), aspirin, paracetamol (acetaminophen), phenacetin, and metamizol (dipyrone) and risk of bladder cancer and their interaction with polymorphisms in drug-metabolizing genes. METHODS: We analyzed personal interview data from 958 incident bladder cancer cases and 1,029 hospital controls from a multicenter case-control study in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Analgesics

Share to Anti-Inflammatory Agents, Non-Steroidal

Share to Aryl Hydrocarbon Hydroxylases

Share to Cytochrome P-450 CYP2C9

Share to Glutathione S-Transferase pi

Share to Odds Ratio

Share to Urinary Bladder Neoplasms

Source

Open in PubMed

Identifiers

PMID: 16985032
DOI: 10.1158/1055-9965.EPI-06-0038

Genes

GSTP1
NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Use of analgesics and nonsteroidal anti-inflammatory drugs, genetic predisposition, and bladder cancer risk in Spain.PMID 16985032Read ↗

Nonsteroidal anti-inflammatory drugs and other analgesic use and bladder cancer in northern New England.Semantic proximity Read ↗

No evidence that polymorphisms in CYP2C8, CYP2C9, UGT1A6, PPARdelta and PPARgamma act as modifiers of the protective effect of regular NSAID use on the risk of colorectal carcinoma.Semantic proximity Read ↗

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.Semantic proximity Read ↗

A meta-analysis of PTGS1 and PTGS2 polymorphisms and NSAID intake on the risk of developing cancer.Semantic proximity Read ↗

Bladder cancer risk from the perspective of genetic polymorphisms in the carcinogen metabolizing enzymes.Semantic proximity Read ↗

Risk factors of symptomatic NSAID-induced small intestinal injury and diaphragm disease.Semantic proximity Read ↗

Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.Semantic proximity Read ↗

COX-1 (PTGS1) and COX-2 (PTGS2) polymorphisms, NSAID interactions, and risk of colon and rectal cancers in two independent populations.Semantic proximity Read ↗

An update on the pharmacogenomics of NSAID metabolism and the risk of gastrointestinal bleeding.Semantic proximity Read ↗

Prospective study of interaction between alcohol, NSAID use and polymorphisms in genes involved in the inflammatory response in relation to risk of colorectal cancerSemantic proximity Read ↗

Synergism interaction between genetic polymorphisms in drug metabolizing enzymes and NSAIDs on upper gastrointestinal haemorrhage: a multicenter case-control study.Semantic proximity Read ↗

No modification of the beneficial effect of NSAIDs on colorectal cancer by CYP2C9 genotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.