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Article

Characteristics of frontotemporal dementia patients with a Progranulin mutation.

Annals of neurology - 1 Sept 2006

Huey Edward D, Grafman Jordan, Wassermann Eric M, Pietrini Pietro, Tierney Michael C, Ghetti Bernardino, Spina Salvatore, Baker Matt, Hutton Mike, Elder Joshua W, Berger Stephen L, Heflin Kyle A, Hardy John, Momeni Parastoo

Abstract excerpt

OBJECTIVE: Mutations in the Progranulin gene (PGRN) recently have been discovered to be associated with frontotemporal dementia (FTD) linked to 17q21 without identified MAPT mutations. The range of mutations of PGRN that can result in the FTD phenotype and the clinical presentation of patients with PGRN mutations have yet to be determined. METHODS: In this study, we examined 84 FTD patients from families not...

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Identifiers

PMID: 16983677
DOI: 10.1002/ana.20969
PMCID: PMC2987739

Genes

MAPT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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