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Article

ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.

Journal of virology - 1 Oct 2006

Orlando Joseph S, Balliet John W, Kushnir Anna S, Astor Todd L, Kosz-Vnenchak Magdalena, Rice Stephen A, Knipe David M, Schaffer Priscilla A

Abstract excerpt

The immediate-early regulatory protein ICP22 is required for efficient replication of herpes simplex virus type 1 in some cell types (permissive) but not in others (restrictive). In mice infected via the ocular route, the pathogenesis of an ICP22- virus, 22/n199, was altered relative to that of w...

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Source

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Identifiers

PMID: 16973544
DOI: 10.1128/JVI.01061-06
PMCID: PMC1617265

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16973544-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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ICP22 is required for wild-type composition and infectivity of herpes simplex virus type 1 virions.PMID 16973544Read ↗

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