Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotyping fetal paternally inherited SNPs by MALDI-TOF MS using cell-free fetal DNA in maternal plasma: influence of size fractionation.

Electrophoresis - 1 Oct 2006

Li Ying, Wenzel Friedel, Holzgreve Wolfgang, Hahn Sinuhe

Abstract excerpt

The determination of fetal point mutations from fetal cell-free DNA (cf-DNA) in maternal plasma is technically challenging due to the preponderance of maternal sequences. It has recently been shown that fetal cf-DNA sequences are smaller than maternal ones and that the selection of small cf-DNA fragments by size fractionation by agarose gel electrophoresis leads to the enrichment of fetal cf-DNA sequences,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Fetal Blood
Share to Fetus
Share to Paternity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Point Mutation

Share to Pregnancy

Share to Prenatal Diagnosis

Share to Sensitivity and Specificity

Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Source

Identifiers

PMID: 16972300
DOI: 10.1002/elps.200600084

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotyping fetal paternally inherited SNPs by MALDI-TOF MS using cell-free fetal DNA in maternal plasma: influence of size fractionation.PMID 16972300Read ↗

Non-invasive prenatal detection of achondroplasia in size-fractionated cell-free DNA by MALDI-TOF MS assay.Semantic proximity Read ↗

Size fractionation of cell-free DNA in maternal plasma and its application in noninvasive detection of fetal single gene point mutations.Semantic proximity Read ↗

Detection of SNPs in the plasma of pregnant women and in the urine of kidney transplant recipients by mass spectrometry.Semantic proximity Read ↗

Non-invasive prenatal diagnosis using cell-free fetal DNA in maternal plasma from PGD pregnancies.Semantic proximity Read ↗

Size fractionation of cell-free DNA in maternal plasma improves the detection of a paternally inherited beta-thalassemia point mutation by MALDI-TOF mass spectrometry.Semantic proximity Read ↗

Detection of Paternally Inherited Fetal Point Mutations for β-Thalassemia Using Size-Fractionated Cell-Free DNA in Maternal PlasmaSemantic proximity Read ↗

Size Separation of Circulatory DNA in Maternal Plasma Permits Ready Detection of Fetal DNA PolymorphismsSemantic proximity Read ↗

Analysis of the Size Distributions of Fetal and Maternal Cell-Free DNA by Paired-End SequencingSemantic proximity Read ↗

Improved prenatal detection of a fetal point mutation for achondroplasia by the use of size-fractionated circulatory DNA in maternal plasma--case report.Semantic proximity Read ↗

Size-based molecular diagnostics using plasma DNA for noninvasive prenatal testingSemantic proximity Read ↗

Detection of restriction enzyme-digested target DNA by PCR amplification using a stem-loop primer: application to the detection of hypomethylated fetal DNA in maternal plasma.Semantic proximity Read ↗

MS analysis of single-nucleotide differences in circulating nucleic acids: Application to noninvasive prenatal diagnosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.