Article
Ubiquitin-proteasome system and Parkinson's disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2006
Olanow C Warren, McNaught Kevin St P
Abstract excerpt
Increasing genetic, pathological, and experimental evidence suggest that neurodegeneration in both familial and sporadic forms of Parkinson's disease (PD) may be related to a defect in the capacity of the ubiquitin-proteasome system (UPS) to clear unwanted proteins, resulting in protein accumulat...
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