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Article

AIG1 affects in vitro and in vivo virulence in clinical isolates of Entamoeba histolytica

19 Mar 2018

Abstract excerpt

The disease state of amebiasis, caused by Entamoeba histolytica, varies from asymptomatic to severe manifestations that include dysentery and extraintestinal abscesses. The virulence factors of the pathogen, and host defense mechanisms, contribute to the outcomes of infection; however, the underlying genetic factors, which affect clinical outcomes, remain to be fully elucidated. To identify these genetic factors...

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PMID: 29554130
DOI: 10.1371/journal.ppat.1006882

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