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Article

Juvenile-onset Parkinsonism as a result of the first mutation in the adenosine triphosphate orientation domain of PINK1.

Archives of neurology - 1 Sept 2006

Leutenegger Anne-Louise, Salih Mustafa A M, Ibáñez Pablo, Mukhtar Maowia M, Lesage Suzanne, Arabi Ali, Lohmann Ebba, Dürr Alexandra, Ahmed Ammar E M, Brice Alexis

Abstract excerpt

BACKGROUND: Mutations in the PTEN-induced putative kinase 1 (PINK1) gene at 1p36 have been involved in autosomal recessive early-onset parkinsonism. OBJECTIVE: To describe the clinical and genetic features of the largest kindred reported to date with early-onset parkinsonism associated with the PINK1 gene. DESIGN: Clinical and genetic study. SETTING: Collaborative study. Patients Eight patients from Sudan with...

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Source

Identifiers

PMID: 16966503
DOI: 10.1001/archneur.63.9.1257

Genes

PINK1
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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