Article
HIV-1 genotypic resistance patterns predict response to saquinavir-ritonavir therapy in patients in whom previous protease inhibitor therapy had failed.
Annals of internal medicine - 7 Dec 1999
Zolopa A R, Shafer R W, Warford A, Montoya J G, Hsu P, Katzenstein D, Merigan T C, Efron B
Abstract excerpt
BACKGROUND: Tests for resistance to HIV drugs are available for clinical use; however, their predictive value has not been fully assessed. OBJECTIVES: To determine HIV-1 genotypic predictors of a virologic response to saquinavir-ritonavir therapy in patients in whom at least one previous protease inhibitor-containing regimen had failed and to compare the predictive value of baseline genotype with that of standard...
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